SYNTHESIS, ANTIMICROBIAL ACTIVITY OF SOME NOVEL SUBSTITUTED THIOPHENE DERIVATIVES
Keywords:
Cyclohexanone, acetaldehyde, cyanoacetamide malanonitrile.Abstract
Various novel substituted thiophene derivatives were prepared by Gewald method using cyclohexanone/acetaldehyde treated with elemental sulphur and active nitriles like ethylcyanoacetate, cyanoacetamide and malanonitrile in presence of base morpholine and solvent ethanol to give corresponding titled compounds in good yields. The synthesized compounds were characterized by physical properties and spectral studies (IR, 1H-NMR& mass) and tested for antimicrobial activity.
Downloads
Download data is not yet available.
Downloads
Published
02-07-2020
How to Cite
1.
B.Satya Sree, A.Lakshmana Rao, M.L.N.T.Amaleswari, M.Udaykiran, M.Sasikala, N.Teja. SYNTHESIS, ANTIMICROBIAL ACTIVITY OF SOME NOVEL SUBSTITUTED THIOPHENE DERIVATIVES. IJRAPS [Internet]. 2020 Jul. 2 [cited 2025 Jul. 6];3(12):380-4. Available from: https://ijraps.in/index.php/ijraps/article/view/77
Issue
Section
Articles